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Sitagliptin Treatment Of Type 2 Diabetes Pharma Intermediates Cas 486460-32-6
Product Details:
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Detailed Product Description
| CAS: | 486460-32-6 | MF: | C16H15F6N5O |
|---|---|---|---|
| MW: | 407.32 | Boiling Point: | 529.9±60.0 °C(Predicted) |
| Density: | 1.61±0.1 G/cm3(Predicted) | Acidity Coefficient (pKa): | 7.20±0.10(Predicted) |
| EINECS: | 690-730-1 |
Sitagliptin Treatment Of Type 2 Diabetes Pharma Intermediates Cas 486460-32-6
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Product Description
Product Name: Sitagliptin
CAS No.: 486460-32-6
English synonyms:Sitagliptinfreebase;(3R)-3-AMino-1-[3-(trifluoroMethyl)-5,6,7,8-tetrahydro-1,2,4-riazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-rifluorophenyl)butan-1-one;(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;Sitagliptin(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-Chemicalbooktriazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;Sitagliptinbase;(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;1,2,4-Triazolo(4,3-A)pyrazine,7-((3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl)-5,6,7,8-tetrahydor-3-(trifluoromethyl)-;Hsdb7516
Molecular Formula: C16H15F6N5O
Molecular Weight: 407.3136
Property: White powder
Assay: 99%
Package: 25kg/drum
Certification of Analysis
| Item | Specification |
| Appearance | White or whitish solid powder |
| Melting metals: | 203.0-205.0°C |
| Specific rotation | N/A |
| High-performance liquid chromatograph HPLC | The retention time of test sample major peak complies to reference standard |
| IR - Infrared spectrometry | The retention time of test sample major peak complies to reference standard |
| Water content | No more than 1.0% |
| Residue on ignition | No more than 0.1% |
| Related impurity | Total impurity no more than 1.0% |
| Any impurity no more than 0.5% | |
| Heavy metal | No more than 20ppm |
| Assay | No less than 9 |
Function&Application
Sitagliptin is an oral antihyperglycemic of the dipeptidyl peptidase-4 inhibitor class. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents for treatment of diabetes mellitus type 2.The benefit of this medicine is its fewer side effects in the control of blood glucose values. While safety is its advantage, efficacy is often challenged as it is often recommended to be combined with other agents such as metformin.
We have complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. We have a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.Our business is based on honesty and mutual trust. Sincerely look forward to establishing long-term mutually beneficial and good cooperation with customers all over the world.
| Packaging Detail |
0.5kgs/Al-Bottle 1.0kgs/Al- Bottle 2.0kgs/Al- Bottle 5.0 kgs/Al-Bottle 25.0 kgs/drum or upon customers' request. |
| Storage | Store in a well-closed container away from moisture |
| Shelf Life | 2 years if sealed and store away from direct sun light. |
| Delivery Detail | within 3 days after get the payment |
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Contact Details
Weifang Ruze New Material Co., Ltd.
Contact Person: Ma
Tel: 86-13583611556
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