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Natural moisturizer Hyaluronic Acid 9004-61-9 Powder High Purification

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Natural moisturizer Hyaluronic Acid 9004-61-9 Powder High Purification

China Natural moisturizer Hyaluronic Acid 9004-61-9 Powder High Purification supplier
Natural moisturizer Hyaluronic Acid 9004-61-9 Powder High Purification supplier Natural moisturizer Hyaluronic Acid 9004-61-9 Powder High Purification supplier

Large Image :  Natural moisturizer Hyaluronic Acid 9004-61-9 Powder High Purification

Product Details:

Place of Origin: Weifang,China
Brand Name: RuzE
Model Number: TC-2019

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 100g, 1kg or As customer request
Delivery Time: 5-10work days
Payment Terms: L/C, T/T, Western Union, MoneyGram
Supply Ability: 500kg/Month
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Detailed Product Description
CAS: 9004-61-9 MF: C14H22NNaO11
MW: 403.31 EINECS: 232-678-0
Product Categories: -;Substrates;Cnbio Mol File: 9004-61-9.mol

Natural moisturizer Hyaluronic Acid 9004-61-9 Powder High Purification


                                             Hyaluronic Acid Powder CAS 9004-61-9


[Product Description]:

Product Name Hyaluronic Acid Other Name Sodium Hyaluronate
CAS No. 9004-61-9 EINECS No. 232-678-0
Molecular Formula C28H44N2O23 PH Value 6.0-7.5
Content 95.0%~105.0 Appearance White powder
Grade Food grade; Cosmetic grade; Medical grade
Molecular Weight <10,000Da (Super Low Molecular Weight)
10,000Da-200,000Da (Low Molecular Weight)
200,000Da-1,600,000Da (Regular Molecular Weight)
>1,600,000Da (High Molecular Weight)



Hyaluronic acid , also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widelythroughout connective, epithelial, and neural tissues.It is unique among glycosaminoglycans in that it isnonsulfated, forms in the plasma membrane insteadof the Golgi apparatus, and can be very large, with itsmolecular weight often reaching the millions. One ofthe chief components of the extracellular matrix, hyaluronan contributes significantly to cell proliferation and migration, andmay also be involved in the progression of some malignant tumors.

Hyaluronic acid is a substance that is naturally present inthe human body. It is found in the highest concentrationsin fluids in the eyes and joints. The hyaluronic acid that isused as medicine is extracted from rooster combs ormade by bacteria in the laboratory. People takehyaluronic acid for various joint disorders, includingosteoarthritis.


(1). Hyaluronic acid has high purification of more than 91%, with D-glucuronic acid content being more than 44%.
(2). Since Hyaluronic acid is fine classified in terms of different molecular weight , it can be tailored for customers with various requirememts.
(3). Protein content in Hyaluronic acid is so low that it can be rarely detected by Bradford method, thus hypersensitivity is prevented when using cosmetics made from Hyaluronic acid;
(4). Hyaluronic acid doesn't contain antiseptic and thickening agent. Hazardous chemicals aren't allowed to be used during production so as to guarantee HA product.
(5). Key equipment and materials are imported for good quality. And Other materials are non-animal, then uncertain infection from animals is avoided so that HA product is guaranteed.
(6). Hyaluronic acid has high safety for the total amount of bacteria can't be detected basically.



Items Specifications
Appearance White powder
Glucuronic Acid 42.0% min
Hyaluronate 93.0% min
Transparency(in 0.1% Solution) 98.0%min
Molecular 0.8-1.5 X 106
Protein 0.1% max
Loss on Drying 3.0% max
Residue on Ignition 20% min
Bulk Density 0.20 - 0.40 g/cm3
PH 6.0 - 7.5
Heavy Metals 10.0ppm max
Arsenic 1ppm max
Lead 1ppm max
Total plate count 1000 cfu/g
Mold and Yeast 100cfu/g
Salmonella Negative
Staphylococcus Aureus Negative
E.Coli Negative
GMO Status Non GMO

Hyaluronic acid Chemical Properties

storage temp. −20°C
solubility H2O: 5 mg/mL, clear, colorless
form Lyophilized Powder
color White
Water Solubility Soluble in water.
CAS DataBase Reference 9004-61-9
EPA Substance Registry System Hyaluronic acid(9004-61-9)

Safety Information

Hazard Codes B
Safety Statements 22-24/25
WGK Germany 3
RTECS MT7250000
F 3-10
Hazardous Substances Data 9004-61-9(Hazardous Substances Data)

MSDS Information

Provider Language
Hyaluronic acid English
SigmaAldrich English
ACROS English

Hyaluronic acid Usage And Synthesis

Hyaluronic Acid Hyaluronic acid is a completely transparent, non-adhesive, water-soluble and grease-free acid mucopolysaccharide. Its molecular weight is between a few hundred thousand to millions, and it makes up the dermis layer of the skin. Its unique molecular structure and physicochemical properties has many important physiological functions inside the body, such as lubricating joints, adjusting vascular permeability, adjusting proteins, diffusing and transporting water electrolytes, and promoting wound healing. Hyaluronic acid has a unique water retention effect and has the best known natural moisturizing properties, making it the ideal natural moisturizer.
Hyaluronic acid is an essential drug in ophthalmic “sticky surgeries”. It is used in cataract surgery, in which its sodium salt remains in the anterior chamber to maintain depth in the anterior chamber and ensure a clear surgical view. It reduces the occurences of postoperative inflammation and complications, thus improving the vision-correcting effects of the surgery. It is also used in complicated retinol detachment surgery. Hyaluronic acid has a low molecular weight and is considered the ideal natural moisturizing agent, so it is used as an additive in high-end makeup and as a moisturizer in creams, gels, lotions, masks, and serums. It is also used medically as a moisturizer to improve moisture retention and lubrication, and it also expands capillaries and improves skin health. For example, hyaluronic acid with a low molecular weight can be used as a lubricant in surgeries (such as knee surgery), while those with high molecular weight can be used as surgical lubricant and as a substitute for vitreous in ophthalmic surgery.
Benefits Hyaluronic acid’s main functions include:
  • Has excellent affinity to water and can regroup water within tissue for better retention and lubrication.
  • Folds to form a three-dimensional network and produces physiological effects, including producing fluid resistance, maintaining water balance and bodily stability, influencing macromolecule solubility, structure, chemical balance and system osmotic pressure, preventing the spread of pathogens, and promote the condensation of collagen fiber secretory substances.
  • Forms polymers with inseparable proteins to maintain tissue shape and size and to ensure reversible tissue compression resistance.
  • Affects macrophages, adherent cells, lymph cells, and natural killer cells.
  • Serves as an important part of interstitial fluid and is mainly metabolized in the liver. Liver fiber activity increases HA synthesis; combined with reduced function during cirrhosis, blood HA levels may increase abnormally.
Uses Synovitis agent (veterinary).



Natural moisturizer Hyaluronic Acid 9004-61-9 Powder High PurificationNatural moisturizer Hyaluronic Acid 9004-61-9 Powder High Purification

Natural moisturizer Hyaluronic Acid 9004-61-9 Powder High PurificationNatural moisturizer Hyaluronic Acid 9004-61-9 Powder High PurificationNatural moisturizer Hyaluronic Acid 9004-61-9 Powder High Purification

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