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PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5

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PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5

China PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5 supplier
PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5 supplier PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5 supplier

Large Image :  PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5

Product Details:

Place of Origin: Weifang,China
Brand Name: Ruze
Certification: COA MSDS
Model Number: 1095173-27-5

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1kg/drum
Delivery Time: 5-7 work days
Payment Terms: L/C, T/T, Western Union, MoneyGram
Supply Ability: 1000kg/week
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Detailed Product Description
CAS: 1095173-27-5 MF: C21H22N6O
MW: 374.43898 Boiling Point: 633.4±55.0 °C(Predicted)
Density: 1.33±0.1 G/cm3(Predicted) Acidity Coefficient (pKa): 11.93±0.10(Predicted)
Color: White Color Powder

Advantage of our API-CAS 1095173-27-5

 

1. High purity

2. Consistent quality for Lorlatinib

3. Competitive price

4. Fast Shipping for Lorlatinib

 

PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5

 

PF-04449913 is an orally available Hedgehog pathway inhibitor that acts by binding Smoothened (Smo) and blocking signal transduction (IC50 = 5 nM). It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model.

 

Item Standard Test Results
Identification A.H-NMR:Comply with the structure Complies
B.LC-MS:Comply with the structure Complies
C.The IR spectrum of sample should be identical with that of reference standard; Complies

D.HPLC-ESI-MS

The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

Complies
Crystallinity meets the requirements. Complies
Loss on drying ≤2.0% 0.19%
Heavy metals ≤10 ppm <10ppm
Water ≤1.0% 0.1%
Sulphated ash ≤0.5%, determined on 1.0 g. 0.009%
Related substances Unspecified impurities: for each impurity ≤0.10% <0.10%
Total Impurity ≤0.5% 0.18%
Purity ≥99.0% 99.7%
Assay 99.0%~101.0% (anhydrous substance). 99.8%
Microbiological Analysis
Total plate count ≤1000cfu/g Complies
Yeast and Moulds ≤100cfu/g Complies
E. Coli. Absent Negative
Salmonella Absent Negative
S.aureus Absent Negative
Storage Preserve in well-closed, light-resistant and airtight containers.

Complies

 

PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5

PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5

 

PF -04449913 Treatment Of Malignant Hematological Malignancies Cas 1095173-27-5

 

 

We have complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. We have a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.Our business is based on honesty and mutual trust. Sincerely look forward to establishing long-term mutually beneficial and good cooperation with customers all over the world.

 

 

Packaging Detail

0.5kgs/Al-Bottle

1.0kgs/Al- Bottle

2.0kgs/Al- Bottle

5.0 kgs/Al-Bottle

25.0 kgs/drum

or upon customers' request.

Storage Store in a well-closed container away from moisture
Shelf Life 2 years if sealed and store away from direct sun light.
Delivery Detail within 3 days after get the payment

Contact Details
Weifang Ruze New Material Co., Ltd.

Contact Person: Ma

Tel: 86-13583611556

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