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Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1

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Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1

China Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1 supplier
Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1 supplier Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1 supplier

Large Image :  Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1

Product Details:

Place of Origin: Weifang,China
Brand Name: RuzE
Model Number: TC-5044

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1kg Alumium Foil Bag
Delivery Time: 5-10work days
Payment Terms: L/C, T/T, Western Union, MoneyGram
Supply Ability: 25kg/Month
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Detailed Product Description
Product Name: Osimertinib Mesylate Synonyms: Mesylate-AZD9291;Osimertinib Mesylate (Tagrisso, Mereletinib, AZD-9291);Osimertinib D6;N-(2-(N-(2-(dimethylamino)ethyl)-N-methylamino)-4-methoxy-5-((4-(1-methyl-1H-indole-3-yl)pyrimidine-2-yl)amino)phenyl)acrylamide Methanesulfonate;Osimertinib Methanesulf
CAS: 1421373-66-1 MF: C29H37N7O5S
MW: 595.71298

Weifang Ruze New Material Co.,LTD a China supplier of AZD9291 Mesylate (CAS No.: 1421373-66-1),CAS 1421373-66-1 offers for your requirements of RND, evaluation, pilots and commercial along with supportive technical package required for evaluation.


Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1

                                                                                                                            

                                                                     AZD9291 Mesylate

 

[PRODUCT NAME]:AZD9291 Mesylate

[CATALOG NUMBER]:ZHY-0002

[CAS NUMBER]:1421373-66-1

[MOLECULAR FORMULA]:C29H37N7O5S

[MOLECULAR WEIGHT]:595.71300

[BATCH NO]: 20190302

[TEST]:SPECIFICATION

[APPEARANCE]: Yellow Solid

[ASSAY]:99%min

[WATER]: 0.5%max


 

Safety Information

HS Code 29339900

 

Osimertinib mesylate Usage And Synthesis

Definition ChEBI: A methanesulfonate (mesylate) salt prepared from equimolar amounts of osimertinib and methanesulfonic acid. Used for treatment of EGFR T790M mutation positive non-small cell lung cancer.
Indications The collection of ibrutinib (Imbruvica(R), Pharmacyclics Inc.), afatinib, and osimertinib represents the small, yet expanding, group of covalent SMKIs. Ibrutinib is a non-receptor Bruton’s tyrosine kinase inhibitor approved for the treatment of relapsed chronic lymphocytic leukemia. Afatinib, approved for NSCLC in 2013 and squamous NSCLC in 2016, is a second-generation irreversible EGFR inhibitor that targets wild-type EGFR, the mutant T790M EGFR, and HER2. Osimertinib (AZD9291), which was approved by FDA in November 2015, is a third-generation irreversible EGFR inhibitor that selectively targets the mutant T790M EGFR. Rociletinib, which shares a high degree of structural similarity with that of osimertinib, is a promising covalent EGFR inhibitor developed by Clovis Oncology aimed for the treatment of patients with EGFR T790M-mutated NSCLC, until the company terminated its development in May 2016 following a negative vote fromthe FDA’sOncologic Drugs Advisory Committee.

 

Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1

Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1

 

Mesylate-AZD9291 Osimertinib Mesylate (Tagrisso, Mereletinib AZD-9291)CAS1421373-66-1


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