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Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%

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Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%

China Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99% supplier
Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99% supplier Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99% supplier

Large Image :  Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%

Product Details:

Place of Origin: Weifang,China
Brand Name: Ruze
Certification: COA MSDS
Model Number: 1454846-35-5

Payment & Shipping Terms:

Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: 1kg/drum
Delivery Time: 5-7 work days
Payment Terms: L/C, T/T, Western Union, MoneyGram
Supply Ability: 1000kg/week
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Detailed Product Description
CAS: 1454846-35-5 MF: C21H19FN6O2
MW: 406.4129632 Boiling Point: 675.0±55.0 °C(Predicted)
Density: 1.42±0.1 G/cm3(Predicted) Acidity Coefficient (pKa): 6.05±0.40(Predicted)
Color: White Color Powder EINECS: 813-704-5

 

Advantage of our API-CAS 1454846-35-5 Lorlatinib

 

1. High purity

2. Consistent quality for Lorlatinib

3. Competitive price

4. Fast Shipping for Lorlatinib

 

Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%

 

PF-06463922

Cas No.1454846-35-5
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
M.Wt406.41
FormulaC21H19FN6O2

 

Loratinib, also known as PF-06463922, is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity. Upon administration, ALK/ROS1 inhibitor PF-06463922 binds to and inhibits both ALK and ROS1 kinases. The kinase inhibition leads to disruption of ALK- and ROS1-mediated signaling and eventually inhibits tumor cell growth in ALK- and ROS1-overexpressing tumor cells. In addition, PF-06463922 is able to cross the blood brain barrier.

 

Product name Lorlatinib
CAS NO. 1454846-35-5
Synonyms Lorlatinib; PF-6463922; 1924207-18-0 (acetate); 2135926-03-1 (maleate); 2306217-6 (hydrate); PF06463922; PF 06463922; PF-06463922; PF-6463922; PF6463922; PF 6463922; (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile
Category Pharmaceutical Raw Materials, Active Pharmaceutical Ingredients, Bulk Drugs, Fine Chemicals.
Purity 99% Lorlatinib
Appearance Lorlatinib powder
Shelf life 2 years for Lorlatinib
Usage Lorlatinib is approved in the US and in Europe for the second- or third-line treatment of ALK-positive metastatic non-small-cell lung cancer (NSCLC).
Storage Lorlatinib should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.

 

 

What is the Lorlatinib (PF-6463922)?

Lorlatinib (PF-6463922) is an experimental anti-neoplastic drug in development by Pfizer. It is a orally-administered small molecule inhibitor of ROS1 and ALK.

In 2015, FDA granted Pfizer orphan drug status for lorlatinib for the treatment of non-small cell lung cancer.

Lorlatinib is able to cross the blood-brain barrier.

 


 

 

 

Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%

Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%

 

Loratinib CAS 1454846-35-5 Antineoplastic Drugs White Crystal Powder Assay 99%

 

 

We have complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. We have a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.Our business is based on honesty and mutual trust. Sincerely look forward to establishing long-term mutually beneficial and good cooperation with customers all over the world.

 

 

Packaging Detail

0.5kgs/Al-Bottle

1.0kgs/Al- Bottle

2.0kgs/Al- Bottle

5.0 kgs/Al-Bottle

25.0 kgs/drum

or upon customers' request.

Storage Store in a well-closed container away from moisture
Shelf Life 2 years if sealed and store away from direct sun light.
Delivery Detail within 3 days after get the payment

Contact Details
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Contact Person: Ma

Tel: 86-13583611556

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